Partial Purification of a Serum Inhibitor of C'1-Esterase
نویسندگان
چکیده
منابع مشابه
Partial purification of a serum inhibitor of C'1-esterase.
The first component of human complement (C’l) has been reported to exist in serum as a proenzyme which can be activated by antigen-antibody aggregates (l-5), plasmin (1, B), and, in a partially purified state, by autocatalysis (6, 7) to an enzyme, C’l-e&erase, capable of hydrolyzing certain synthetic amino acid esters, notably N-acetyl-L-tyrosine ethyl ester (6-8), and interacting with the four...
متن کاملPartial purification of the serum trypsin inhibitor.
The serum trypsin inhibitor has been studied by many investigators since Lansteiner (1) associated it with the albumin fraction by salt fractionation as did Smith and Lindsley (2) by the electrophoretic separation of serum. Both Christensen and MacLeod (3), and MacFarlane and Pilling (4), also associated the trypsin inhibitor with the albumin fraction but differentiated it from the plasmin inhi...
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angioedema is characterized by recurrent, circumscribed, solitary or multiple subcutaneous and mucosal swelling, involving the extremities, face, larynx, bowel wall. angioedema is due to hereditary or acquired varieties of c1 esterase inhibitor (c1inh) deficiency. a case of atypical acquired angioedema in a 49-year old man, responding favourably to cinnarizine and alcohol abstinence, is present...
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somal dominant disorder that results in episodes of acute edema in various organs, including the gastrointestinal tract, skin and larynx. It is estimated to affect about 1 in 50 000–100 000 people. The symptoms, including abdominal pain, laryngeal edema and subcutaneous edema, usually begin in childhood and persist throughout life with unpredictable severity. Hereditary angioedema is classified...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1961
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)63283-7